Huge celebrations are planned for the anniversary event, which is to be hosted by Peter Kay, including a duet between Florence from the Magic Roundabout and Jamie from The Magic Torch.
Robbie Williams, Amy Winehouse and Pete Docherty are jointly to receive the honorary award for Lifetime Contribution to Rehabilitation Centres, and boy band JLS are up for Best Crowd Breakthrough following their oversold Birmingham gig.
Lily Allen is the bookmaker's favourite to win Best Female Act, against strong opposition from Lady GaGa. However, Lady GaGa is conversely also the favourite for the Best Male Act award and Best Overall Package.
Cheryl Kerl is hotly tipped for the Most Talentless Eye-Candy gong, and has also received a nod for Most Stupid Outfit, though she faces strong competition from comeback king Robbie Williams.
Peter Kay is to present the awards, although rumours that he will be doing a group performance of 'Amarillo' with the nominees remain unconfirmed.